Global Rheumatoid Arthritis Therapeutics Market Assessment, By Type of Molecule [Biopharmaceuticals, Pharmaceuticals], By Drug Class [Non-Steroidal Anti-Inflammatory Drugs, Corticosteroids, Disease-Modifying Antirheumatic Drugs, Janus Kinase Inhibitors, Biologic Agents, Others], By Sales Channel [Prescription, Over the Counter], By Region, Opportunities and Forecast, 2017-2031F

Global rheumatoid arthritis therapeutics market is projected to witness a CAGR of 5.58% during the forecast period 2024-2031, growing from USD 30.05 billion in 2023 to USD 46.39 billion in 2031. 

Rheumatoid Arthritis Therapeutics Market Share, Growth & Forecast 2031

Global rheumatoid arthritis therapeutics market is projected to witness a CAGR of 5.58% during the forecast period 2024-2031, growing from USD 30.05 billion in 2023 to USD 46.39 billion in 2031. The market&rsquo;s growth is bolstered by the rising cases of rheumatoid arthritis, increasing research activities to improve the understanding of the disease, and growing approvals from different regulatory bodies across the globe. The expansion of the geriatric population is also augmenting the cases of rheumatoid arthritis. As per the World Health Organization (WHO) estimates,&nbsp;one in six people across the globe will be sixty or older by 2030, and by 2050, approximately 2.1 billion people will be sixty or older. Rheumatoid arthritis affects the synovial joints and causes inflammation that can result in loss of function and joint damage over a period of time.
Additionally, increasing the provision of approvals for drugs for rheumatoid arthritis by different regulatory bodies ensures that patients worldwide have access to the necessary medication. In October 2024, Alfasigma S.p.A. received the green light for the commercialization of Jyseleca, a JAK1 drug used for ulcerative colitis and rheumatoid arthritis, following the approval received from the European Medicines Agency. The transfer of marketing authorization for the drug in the European Union was completed after the company purchased the medication for USD 186 million.
Moreover, the growing acceptance of biosimilars, the economically efficient alternatives to biologic drugs with similar therapeutic effects, bolsters the global rheumatoid arthritis therapeutics market size. Major pharmaceutical companies actively invest in approving and developing new biosimilars and biologics, positively influencing the market&rsquo;s growth. Additionally, different research organizations and market players across the globe are actively investing in developing novel therapies that offer fewer side effects than traditional therapies. They also engage in collaborations by pooling their resources and expertise; the organizations can reduce the time required for drug development and easily address the unmet medical requirements of the patients.&nbsp;
<h2>Increasing Prevalence of Rheumatoid Arthritis Boosts Market Demand</h2>
The rising cases of rheumatoid arthritis can be attributed to the expansion of the aging population and changing lifestyles. The increasing disease burden is augmenting the global demand for rheumatoid arthritis therapeutics. As per the estimates of Johns Hopkins&nbsp;University &amp; Medicine, rheumatoid arthritis has a prevalence of 1% to 2%, along with a worldwide distribution. The prevalence of the disease is approaching 5% among women who are older than 55. Autoimmune disease is characterized by the inflammation of joint tissue and exhibits deformation of small joints, pain, and swelling in approximately half of the patient population. Additionally, the development and availability of sensitive testing methods allow patients to receive an early diagnosis, further propelling the requirement for rheumatoid arthritis therapeutics. After the detection of the condition, early treatments such as immunosuppressive drug therapy and nonsteroidal anti-inflammatory drugs are initiated. Additionally, women are more susceptible to the disease as the female immune cells produce more inflammatory cytokines, proteins that control immune cell activity and control inflammation.
Investments in Research Activities Support Market Expansion
The increasing emphasis on research activities for addressing the complexities of the disease and the discovery of novel treatments is aiding researchers in developing advanced therapeutic solutions for rheumatoid arthritis and providing lucrative growth opportunities to the market. One of the promising research areas in the disease is the exploration of biological agents that are responsible for targeting unique immune pathways that play a role in inflammation. In July 2024, SetPoint Medical Corporation announced positive topline results for the RESET-RA clinical study. The clinical study evaluates the use of the SetPoint System as a potential neuroimmune modulation treatment for individuals with moderate to severe rheumatoid arthritis who are intolerant to targeted synthetic or biologic disease-modifying anti-rheumatic drugs or incomplete responders. A significant portion of the patient population suffering from rheumatoid arthritis is either intolerant to the approved treatment options available or adequately responding to them. Moreover, the approved immunotherapies also have severe immunosuppressive risks that can result in low treatment adherence, safety concerns, and poor patient satisfaction. Such clinical research studies are expected to augment the development of therapeutic systems that improve treatment outcomes by increasing patient adherence, among others.
<h2>Biopharmaceuticals Account for Significant Market Share</h2>
The segment's expansion can be attributed to the increasing research studies showcasing the different benefits associated with various biopharmaceuticals. According to an article published in the JAMA Network of the American Medical Association in June 2024, treatment sequences initiated by biosimilar disease-modifying antirheumatic drugs (DMARDs) were shown to be cost-effective in comparison with treatment sequences initiated with leflunomide in patients suffering from rheumatoid arthritis as per a study conducted by a team of researchers from the University of Hong Kong. Such studies highlight the financial feasibility and benefits associated with biosimilar drugs, resulting in their increasing demand.
Additionally, the comparative effectiveness analysis published in the Rheumatology Journal of the Oxford University Press in September 2023&nbsp;showed that patients who were switched from etanercept originator to biosimilar had similar drug persistence and disease activity as those patients who remained on the originator, thus indicating nonmedical switching does not have a detrimental effect on treatment outcomes. The study was conducted with the help of data from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis (BSRBR-RA), which tracks patients with rheumatoid arthritis who start targeted or biologic DMARDs.
<h2>North America Holds Major Market Share</h2>
The expansion of the market in North America can be attributed to the growing prevalence of rheumatoid arthritis in the region, the strong presence of leading market players and research organizations, the rapid growth of the aging population, and the growing emphasis on personalized healthcare. As per the estimates of Johns Hopkins&nbsp;University &amp; Medicine, the average annual incidence of rheumatoid arthritis in the United States is 70 per 100,000 annually. Additionally, the United States Food and Drug Administration (USFDA) is providing approvals for generic drugs for rheumatoid arthritis to increase patient access. In August 2023, Zydus Lifesciences Limited received final approval from the USFDA for manufacturing and marketing their generic suppositories indicated for moderate to severe rheumatoid arthritis. Approval has been given to Zydus for marketing and manufacturing their Indomethacin suppositories at 50 mg strength. Indomethacin suppositories are anti-inflammatory and non-steroidal drugs indicated for rheumatoid arthritis, including moderate to severe ankylosing spondylitis, acute flares of chronic disease, moderate to severe osteoarthritis, acute gouty arthritis, and acute painful shoulder. Additionally, the rising investments from the leading market players in the region towards novel product development and launches and enhancement of their research and development capabilities are further propelling the availability of novel therapeutic solutions in North America, providing lucrative growth opportunities to the rheumatoid arthritis therapeutics market.
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Future Market Scenario (2024-2031F)
As per the global rheumatoid arthritis therapeutics market analysis, the market is expected to witness significant growth in the coming years due to the rising cases of rheumatoid arthritis, increasing awareness about the different treatment options, increasing innovation in therapies, and rising shift towards personalized medicines. According to the estimates of an article published in The Lancet of Elsevier Ltd.&nbsp;in October 2023, the number of cases of rheumatoid arthritis is forecasted to increase by 80.2% between 2020 and 2050, and 31.7 million individuals will be living with the disease by 2050 across the globe. Additionally, different healthcare and government organizations are also working on increasing awareness about the impact of treatment adherence and early diagnosis on patients with rheumatoid arthritis.
Moreover, various healthcare organizations are also investing in treatment programs for healthcare professionals to ensure they are updated on the advancements in the treatments for rheumatoid arthritis. Such efforts are expected to bolster the demand for the global rheumatoid arthritis therapeutics market in the coming years. Regulatory bodies, healthcare professionals, and pharmaceutical companies are expected to play a crucial role in allowing for a patient-centric and effective approach to treating rheumatoid arthritis and ensuring the availability of the required therapeutic solutions.
Report Scope
&ldquo;Rheumatoid Arthritis&nbsp;Therapeutics&nbsp;Market Assessment, Opportunities and Forecast, 2017-2031F&rdquo;,&nbsp;is a comprehensive report by Markets and Data, providing in-depth analysis and qualitative and quantitative assessment of the current state of global rheumatoid arthritis therapeutics market, industry dynamics, and challenges. The report includes market size, segmental shares, growth trends, opportunities, and forecast between 2024 and 2031. Additionally, the report profiles the leading players in the industry, mentioning their respective market share, business models, competitive intelligence, etc.
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Details
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Base Year of the Analysis
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2023
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Historical Period
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2017-2022
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Forecast Period
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2024-2031
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Projected Growth Rate
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CAGR of 5.58% between 2024 and 2031
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Revenue Forecast in 2031
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USD 46.39 billion
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Segments Covered
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Type of Molecule, Drug Class, Sales Channel
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Regions Covered
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North America, Europe, South America, Asia-Pacific, Middle East and Africa
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Key Companies Profile
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AbbVie Inc., Pfizer Inc., Bristol Myers Squibb Company, Novartis AG, F. Hoffmann-La Roche Ltd, Amgen Inc., Bayer AG, Boehringer Ingelheim International GmbH, Eli Lilly and Company, Johnson &amp; Johnson Services, Inc.
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Customization Scope
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15% free report customization with purchase
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Pricing and Purchase Options
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Avail the customized purchase options to fulfill your precise research needs
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Delivery Format
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PDF and Excel through email (subject to the license purchased)
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In the report,&nbsp;global&nbsp;rheumatoid arthritis&nbsp;therapeutics&nbsp;market&nbsp;has been segmented into the following categories:&nbsp;
<ul>
<li>By Type of Molecule
<ul>
<li>Biopharmaceuticals
<ul>
<li>Biologics</li>
<li>Biosimilars</li>
</ul>
</li>
<li>Pharmaceuticals</li>
</ul>
</li>
<li>By Drug Class
<ul>
<li>Non-steroidal Anti-inflammatory Drugs (NSAIDs)</li>
<li>Corticosteroids</li>
<li>Disease-Modifying Antirheumatic Drugs (DMARDs)</li>
<li>Janus Kinase (JAK) Inhibitors</li>
<li>Biologic Agents</li>
<li>Others</li>
</ul>
</li>
<li>By Sales Channel
<ul>
<li>Prescription</li>
<li>Over the Counter (OTC)</li>
</ul>
</li>
<li>By Region
<ul>
<li>North America</li>
<li>Europe</li>
<li>Asia-Pacific</li>
<li>South America</li>
<li>Middle East and Africa</li>
</ul>
</li>
</ul>
Key Players Landscape and Outlook
Various market players are actively working on increasing the affordability of drugs for treating rheumatoid arthritis and boosting their production. In December 2023, the Institute of Drug Technology (Farmanguinhos/Fiocruz) and Pfizer Inc. signed a technology transfer agreement for producing the generic version of Xeljanz, tofacitinib citrate. The partnership aims to increase the public&rsquo;s access to medications necessary for treating immune-mediated inflammatory diseases, including rheumatoid arthritis, and strengthen national production. Such partnerships are expected to improve the patient population's access to healthcare and pharmaceutical products and services in developing countries.
Additionally, in September 2024, Eva Pharma and Eli Lilly and Company announced that they had entered an agreement to enhance access to baricitinib to patients in low-to-middle-income countries in Africa. Under the agreement, the companies aim to provide 20,000 African patients access to the drug by 2030. Baricitinib is used to treat atopic dermatitis, rheumatoid arthritis, and alopecia areata, among others. The collaboration is also a part of Eli Lilly&rsquo;s 30x30 initiative, which aims to improve access to healthcare facilities for 30 million individuals living in resource-limited areas.
Key Players Operating in Global Rheumatoid Arthritis&nbsp;Therapeutics&nbsp;Market are:
<ul>
<li>AbbVie Inc.</li>
<li>Pfizer Inc.</li>
<li>Bristol Myers Squibb Company</li>
<li>Novartis AG</li>
<li>Hoffmann-La Roche Ltd</li>
<li>Amgen Inc.</li>
<li>Bayer AG</li>
<li>Boehringer Ingelheim International GmbH</li>
<li>Eli Lilly and Company</li>
<li>Johnson &amp; Johnson&nbsp;Services, Inc.</li>
</ul>
Markets and Data report answers the following questions:
<ul>
<li>What is the current and future market size of the product/service in question globally or specific to different countries?</li>
<li>How are the markets divided into different product/service segments and the market size and growth of each segment?</li>
<li>What is the market potential of different product segments and their investment case?</li>
<li>How are the markets predicted to develop in the future and what factors will drive or inhibit growth?</li>
<li>What is the business environment and regulatory landscape specific to the product/service?</li>
</ul>
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Global Rheumatoid Arthritis Therapeutics Market Assessment, Opportunities and Forecast, 2017-2031F

The market’s growth is boosted by the rising cases of rheumatoid arthritis across the world due to the expansion of the aging population and changing lifestyles, rising investments in research activities, and growing efforts of the market players to ensure the availability of therapeutic solutions.

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